Boston has literally dozens of colleges! One could get a Master's degree in practically anything. Not only that, it has lots of tech companies, bio companies, and (even more, it seems) biotech companies.

We've also got Mudd folk (iluvsheep, zwilichkl, fabricant, leech all live nearby, there are some others around too) and piles of cool non-Mudd folk (7+ within 2.5 blocks of my house). We have games nights on order of 3 times a week, drawing on what I will estimate is one of the best game collections around. There's good rock climbing, indoors and outdoors - iluvsheep is climbing a couple times a week. There are interesting small towns up and down the coast as well as lots of hiking options (from the very low key to the fairly energetic).

Massachusetts is full of shiny things to do: New England Pirate Faire, Roller Derby, and a Tango Festival are all this weekend, along with dozens of other events. We've got a world class aquarium, several world class museums, the museum of bad art for balance, a large and active kink scene (or so I'm told) and sports (for people who like that sort of thing).

That's all I've got off the top of my head - more as I think of things. :)